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Fulvic Acid in Shilajit Resin

Shilajit Resin is composed of mainly humic substances, including fulvic acid, they account for around 60% to 80% of the total nutraceutical compound plus some oligoelements including selenium of antiaging properties. The humic substances are the results of degradation of organic matter, mainly vegetal substances, which is the result of the action of many microorganisms. Components are divided operationally in humins, humic acid, and fulvic acids according to their solubility in water at different pH levels.

Humins are not soluble in water under any pH condition. Humic acid is soluble in water under alkaline conditions and has a molecular weight of 5–10 kDa. Fulvic acid is soluble in water under different pH conditions, and because of its low molecular weight (around 2 kDa), it is well absorbed in the intestinal tract and eliminated within hours from the body. It is likely that the curative properties attributable to shilajit are provided by the significant levels of fulvic acids that shilajit contains, considering that fulvic acid is known by its strong antioxidant actions and likely has systemic effects as complement activator.

Recent studies on the composition of Andean Shilajit in Chile have evidenced an ORAC index between 50 and 500 Trolox units/g of material, which is substantially higher than Noni and blueberries (Quinteros et al., unpublished data). In this context, shilajit is a powerful antioxidant phytocomplex.This phytocomplex is known by its properties such as antioxidant, anti-inflammatory, and memory enhancer. Novel investigations indicate that fulvic acid is an antiaggregation factor of tau protein in vitro, which projects fulvic acid as a potential anti-Alzheimer’s disease molecule.

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